Upsides/downsides to a Kamala Harris 2020 Democratic presidential bid?

[Okay, maybe Mike Johnson is a competent parliamentarian.]

Upsides=
She would be the first female President.
She was a national leader on a key issue (justice reform) before she became Senator.
She is likely to excite liberals with her voting record.
The media seems to like her.

Downsides=
A San Francisco politician may be a tough sell in Ohio.
Her private life isn't very appealing (no kids, married a rich lawyer at 49, once dated a prominent politician 30 years her senior.)

Which is of course deeply unfair considering whom she'd be running to unseat.