This is about one thing and one thing only.
Making it easier to put a republican in the white house.
Actually union busting moves by the GOP in states like Wisconsin, Ohio, and yes even Indiana, make those states all the likelier to vote Democrat.
Perhaps in the short term. I believe the OP is referring to the fact that unions are a major source of campaign funds for the Democratic Party.
I've never really understood how "right to work" is fair at all. If you don't want to be a member of a union, you're certainly allowed to quit your unionized job and go find non-unionized work.