I think his point was that voters who are frustrated and unhappy should stop electing the same people over and over again, i.e. try something new for once. Baltimore is a monolithic left-wing oligarchy, and it hasn't really served them well.
Exactly.
So they should instead vote for a party that only mentions urban centres as a scare story to whip up their base? People won't just vote against their interest for a party that explicitly dislikes them, never mind how long Democrats have been in charge.
And I do feel nervous that many areas are one-party states, but the modern GOP is not a party interested in cities. Perhaps that is why electoral reform will be helpful.