Probably not.
Party fatigue has been consistent in the last 20+ elections (even when parties win a third term it's by a smaller margin than before.)
The 2010 and 2014 elections gave Republicans a strong bench.
Clinton's struggles against Sanders highlight her flaws as a candidate.
The self-inflicted wounds are unlikely to end when she holds an office with even more scrutiny than before.
Really, if that were true, Republicans would not have won so many landslides between 1968 - 1988. Even Carter, the sole Democratic win during that period, just barely won with a 2pt or less margin after that whole Nixon fiasco. Considering how much Nixon cost Republicans across the country in state legislatures/Congress, you would think if people were turned off by Republicans they would have gave him more votes. Also, Bush 41 still won by an EV landslide (though his popular vote would probably be considered one today), and Bush was no Reagan.