Portman can still win I am just waiting for that brutal ad campaign that tanks Strickland in the end. Also, in a debate I could see Portman eviscerating Strickland on his record. Ohio will be reelecting Portman.
Not with Trump carrying down GOP ticket he can bring Portman, Grassley and Toomey down
2016 maybe a 2004 neutral election but Clinton narrowly winning or a 2012 winning in a landslide. But 2016 maybe the first time that Dems have duplicated am electoral map. But Dems can have a wave Senate seats without winning House
As far as 2018 goes, very little as far as impeachment is concerned without the Senate. If Clinton stays near 47-49% approvals D's will be fine