Is Graham seriously going to try to win a 60% Romney district? She really should retire and not embarrass herself. We need her in 2018 after all.
Announcing your retirement after spending just over one year in public office wouldn't be the most promising start to a future race. It'd be easy fodder for the GOP if she cynically abandoned her constituents the moment things looked difficult for her.
If the district is drastically altered, it wouldn't be "abandoning her constituents", because they never elected her in the first place. "Things looked difficult" in 2014, with her having to win a Republican district in a Republican wave year, and she succeeded when very few thought she would. But there's a difference between difficult and impossible.
Of course, I realize you want her to run and get stomped in the hopes that it will remove her as a threat. I'd be scared of her too if I was a Florida Republican.