The section of the article with anonymous Illinois Dems fretting about holding the seat in 2010 is rather laughable. Anyone with a (D) after his or her name would hold this seat. The 2006 gubernatorial race proves that.
It's not impossible that in 8 years that the GOP could beat Jackson in IL, moreso than the rest of potential candidates.
Not impossible, no, but that assumes that the GOP would even have a bench in the state at that point. It's dwindling fast; could any Illinois Republican rise fast enough to challenge even the weakest Dem? They're going to have Rep. Aaron Schock, who might have some future potential, but, really, the U.S. Senate is a bit ambitious for Illinois Republicans at this point.