Politics aside- would you rather live in a blue state or a red state?

[Skill and Chance]

Personally I like living in a blue city in a red state.

I think this is the best of both worlds.  For a variety of reasons, it is easier to get ahead in business in a red state, but you want to live in a place where the locals just ignore the ding-dongs and treat everyone with respect.

[Skill and Chance]

Keep in mind that we are generally talking about the difference between 60/40 one way and 40/60 the other way.  Or 2:1 in the most extreme (UT,OK,HI,VT) cases.  That leaves a substantial base of people who agree and disagree with you to interact with.  You can still find an vegan society in West Texas or a megachurch in San Francisco if you really want to.

[Skill and Chance]

Yes, it does get pretty bad at the rural conservative extreme.  The 4 Obama voters in King County, TX probably value their anonymity way to much to ever get together for a 2012 victory party.

I think you have to add a libertarian/populist or religion dimension to find the worst fits.  You really wouldn't enjoy being a left-libertarian agnostic in Alabama or a Evangelical SoCon R in Massachusetts.  But some union D's would fit in better in KY than CA and some libertarian R's would fit in better in CA than KY.