Yes. The GOP as we've known it is dead.
The Dems will be a free trade, pro immigration party going forward and the Republicans will be protectionist and nativist. It's amazing it's taken this long to change giving that the GOP base doesn't give a damn about trade and immigration reform despite voting for it for decades.
The southwest moves more towards the Democrats (Nevada, Colorado, New Mexico, and Arizona) while the Midwest and Rust-Belt goes more towards the GOP (Pennsylvania, Michigan, Ohio, Iowa, and maybe Wisconsin).
It's the only realignment possible this time.
There's basically no chance Wisconsin goes GOP. They hate Trump.
Yes, but Wisconsin dislikes Hillary too -- she lost big here to Bernie by nearly the same margin by which Trump lost to Cruz.