If conservatives go gunning for Snowe and force her to jump the GOP ship, I wonder how long before they go for Susan Collins. She's only a smidge less liberal than Snowe and isn't the state political institution like Olympia either.
From what I've read on a Maine political message board, Collins has campaigned for local (like state legislative) Republican candidates more significantly than Snowe. She's also willing to give "red meat" speeches at Republican state conventions that I doubt Snowe gives. When it comes to support of a politician, in a primary or general election, there's more to it than one's voting record.
If Snowe leaves the Senate before Collins, for whatever reason, I'm sure some conservatives will (still) talk about getting a primary challenger to Collins or even supporting a Democrat to get rid of her (they already do and have since the 2002 election), but I doubt anything would come of it. But I don't see Snowe's and Collins's situation as identical.