I'll do the major Roseanne Characters (at least from Dan/Roseanne's formative years to the second to last season which was 1996:)
Roseanne Conner:
1968-Not able to vote due to not being 21. See her supporting McCarthy and later HHH.
1972- McGovern
1976-Carter
1980-Carter
1984-Mondale
1988-Dukakis (She had an epic jab at Bush during Season 1 more or less mocking his attitude/persona.)
1992-Clinton or Perot
1996-Clinton
Rosie was always a hippie and leftist. Seeing her being big for McCarthy or RFK then supporting HHH in 68, diehard for McGovern and Carter in 76 and 80. See her voting Mondale because of Regan-omics plus Ferraro. 1988 on she would be a solid dem minus 1992. But def seeing her staying Dem since 2000.
Dan Conner:
1968-Same as Rosie. HHH?
1972-Nixon?
1976-Carter
1980-Reagan
1984-Reagan
1988-Bush
1992-Clinton or Perot
1996-Clinton
Dan "died" in 1996 but if want to BS it with the final season I could see him voting for Bill. 1992 he def wouldn't vote for Bush due to the recession killing his shop. Before then I see him being a Reagan Democrat. If he lived he would have voted for Dubya in 2000, 04 prob Libertarian or Kerry, 08/12 def Obama.
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Jackie Healey:
1968-Nixon
1972-Nixon
1976-Carter
1980-Reagan
1984-Reagan
1988-Bush
1992-Clinton
1996-Clinton
See Jackie being 2 versions. The early less idiotic one which won Laurie Metcalf the emmy one year and the goofy Don Knotts style Jackie. I see her voting Republican in her less silly days except in 76. When she gets goofy and becomes gay in Roseanne's alternate reality I see her heading left from 1992 on.
Becky Conner Healey:
1988-Bush
1992-Perot?
1996-Clinton
Becky's tough because of how dramatic of changes her character went through. The early serious Becky I see being very tight and conservative but by 1992 I see her loosening up and changing dramatically as a person. More liberal and less tight, plus they got a hotter actress too so that didn't hurt
1992's iffy because the first Becky is there but by 1996 I see Becky 2 going with Clinton. 2000's tough because her character wasn't ever set in stone but I see her going for Dubya as well as 04 before going for Obama in '08 and '12.
Darlene Conner Healey:
1988-Bush
1992-Perot or didn't give a care.
1996-Nader
Darlene's the most dramatic due to how much Sarah Gilbert changed as a person and her influences on the chather. She started as a tomboy who was very much like Dan so I see her supporting Bush Sr at least in 1988. By 1992 she was heading into that goth phase and shut out the rest of the world. See her maybe support Ross due to his outsider status but I can easily see her not giving a crap either. By 1996 she was out of the silly phase and was herself again albeit a major liberal. Don't see her going for Clinton due to his center based polices so I see her as a Green for Nader.
See her voting for him at least through 2004, and in 08/12 see her voting Obama.