Will Mitt Romney win Massachusetts?

[Mechaman]

I think he will, but in a small margin.

But if he loses, he might as well throw in the towel considering, hardly any candidate loses their home state and wins the entire election. 

That is because, in most recent elections, the candidate is from a state that isn't solidly pro-opposition party.
Losing Massachusetts, a solid D state since like forever, isn't going to mean he's dead come election day.