Hillary Clinton/ Michael Bennet
Clinton's the likeliest nominee. Bennet looks like a really good match on paper. The biggest issue is what it means for his seat, but he otherwise has the ideal resume for Hillary Clinton's running mate (White guy in his early 50s, Westerner, Swing State Senator for eight years, Policy expertise on education.)
Rand Paul/ Scott Walker
Paul's more likely to run than any of the other potential top-tier candidates, so he's more likely to be the nominee than Jeb, Christie, Rubio, Walker or Ryan. I have no idea who he would pick as a running mate. Walker seems like a possible fit (a midwestern swing state Governor to show what Republicans in the executive office are like) and he seems to be among the most interested in national office.