I hope she runs. She won't win (that for sure), but it's time for democrats to start running ON Obamacare (see: Mark Pryor) and not AGAINST it, even in republican states. Because those democrats will probably lose this year, but if they really think Obamacare is a success and Americans will like it sooner than later, supporting it now would help them for future races, don't you think?
Oh, and I want to see the Kansas Tea Party ranting about how bad Sebelius is, too (specially the Westboro Church members). There may even be some GOP Congressmen saying "nice" and "not-misogynist-at-all" things about Sebelius. That may help in other races.
Best to run her in 2018 after Brownback peaces it. You know, after people forget about Obamacare.