I prefer non-chains, but if I had to choose, it would probably be Pizza Hut, with Cici's in a close second. The only chain in my hometown is Little Caesars, which is good in a pinch, but far from my preferred choice.
Shockingly, I've never had Domino's, Papa John's, or the others on this list. There's a Papa John's on my college campus, but I would not want to go there simply because the name and TV commercials creep me out. Papa John is the creepiest fast food mascot next to Ronald McDonald, in my opinion.
I don't mind the commercials for Papa John's, I just mind the pizza. My campus' athletics hall/basketball court serves it for games and I hate it. Only reason I have for eating it is because obviously my life's bad enough that I work there and can usually get some for free after half-time.