A public option and ACA-style markets with a mandate along with the repeal of tax benefits for company insurance would probably work better with less effort.
As awesome as the end result of single-payer would be, it would be a nightmare to implement.
Edit:
Yeah, but the financial industry didn't stop existing. It grew back.
People will literally have to be retrained to take different jobs.
There could be deductions and vouchers for education and training. If people could be retrained for jobs during the Great Depression then surely they could be retrained today. It's possible, it would just take a lot of political courage and cooperation.