Grayson and DWS will lose. Both are too partisan and are only in congress because their districts were drawn specifically for them.
It's not as if Mr. Rubio is terribly unpopular, or scandal-ridden, or anything of the sort. Democrats need Murphy or Graham to win, and that's a fact. (Heck, I'd be willing to vote for either one, as they're both in the more conservative side of the democratic party, and Rubio's hardly some moderate stalwart and is willing to flip-flop solely for political gain.)
So, a partisan Republican can win a U.S. Senate seat but the same is not true of a partisan Democrat?
Sherrod Brown and Claire McCaskill have won in purple states when all they do is bash Republicans.
But how did they get there? It took a wave. So it would take either a Patrick Murphy + flawless campaign + Rubio stumble in a neutral environment, or a national wave carrying a generic Dem to get across the finish line for Democrats.
DWS is the worst. She's in it for herself and not the team. I hope she gets primaried in her district, and never runs for Senate.