Your Grandparents vs Your Grandparents.

[Indy Texas]

Maternal Grandparents: a moderate Rockefeller Republican (grandmother) and a fiscally conservative Republican who is indifferent to most social issues (grandfather) (R)

Paternal Grandparents: weren't American; if I attempted to shoehorn their political views into a US context, they'd probably be very economically populist, and conservative to indifferent on most social issues (D)

To make such tickets plausible, let's assume the election was some time in the 1960s:

Perhaps something like this.