Clinton wins 2016 nomination, loses GE to Jeb Bush. is Warren the 2020 favorite?

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I'm sure she'd be leading some of the opinion polls in 2017, but I'm not sure a 71-year-old Elizabeth Warren would even want to run in 2020.

I don't agree.  and if Sanders ends up beating Hillary in one or two early states and causing drama, she'll have every reason to believe she can take on anyone in a national primary and have every chance to win.  Hillary is the lone Heir to the Throne alive in the Dem party; they are rarer with the Dems than with the GOP.

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My guess:  Sen. Kristen Gillibrand (D-NY), but other possibilities include Governor Andrew Cuomo (D-NY), Governor Terry McAuliffe (D-VA), or Sen. Amy Klobuchar (D-MN).

Cuomo and McAuliffe would be non-starters.  

Cuomo's aspirations have to be taken down a peg, given the past year he's had.  he just needs to buckle down, not get arrested, and stay NY Governor for as long as he can.  from there, the chips will fall where they fall.

his best shot probably would have been if Obama lost in 2012, coming around here in 2016.  he would have governed slightly differently, though the corruption thing would have 100x more flashlights around it, perhaps it was secretly a gift from God.  (and he still wouldn't, couldn't have run if Hillary ran)