Is there even a way to truly know the main reasons behind that epic loss? I see a lot of decent suggestions here but it's all over the place. Perhaps a combination of them?
I think Obama/Democrats had/have a severe messaging problem. Democrats actually cut taxes for most people in 2009-2011 and I think some minor cuts after... but did people even realize this? The bank bailout - why were Democrats blamed for this? Nearly half the country in 2010 thought TARP was passed under Obama. This ignorance is a major failure on the part of Democrats. ObamaCare during a recession? Honestly that was the
wrong time to introduce such a social program. He shouldn't have spent so much political capital on healthcare reform during a recession/recovery. It's really sad that Obama helped ruin our prior success for such a weak bill.
http://www.pewresearch.org/daily-number/was-tarp-passed-under-bush-or-obama/I really like Yankee/muon2's take as well. I also believe that Obama accelerated
(and later finalized) the Southern realignment as well - something that was always going to happen, but just happened faster for various reasons, with, imo, race included.
My lazy opinion: Perfect storm of numerous issues/mistakes by Democrats/Obama
+ state of economy