As a part-time Bond buff, let me break this one out.
Certainly all the cold war USSR/Russia-tied villains (Klebb, Kristatos, Zorin, etc.) would support Trump, the moment they saw he likes Putin.
Most of the others may consider him, with a few exceptions:
Kamal Khan would want to support him, but would be deported, as an illegal immigrant, before the vote.
He would also have serious concerns about Trump being anywhere close to Octopussy (in case of accidental grabbing).
Mr. Big would not go there, since the African Americans do NOT like Mr. Trump.
Sanchez would be concerned about the effects of the wall with Mexico, on his business. He would pick Johnson instead (for his expertise on Mexico).
Elliott Carver would be too busy putting his MSM empire to work on behalf of Trump's opponent.
Blofeld (in Diamonds are Forever) would not, as he would consider Trump a direct casino competitor.
And Wint and Kidd (also from DAF) would be your proverbial undecided voters. They would appreciate Trump's sadism but would question his support of gay rights.