Will Hillary Clinton run in 2012 while being Secretary of State?

[The Ex-Factor]

Politics is crazy. In 1991, if you have said that the next three Presidents would be an unknown Governor from the South who would defeat the massively popular Bush/Quayle administration....

Depends on what you mean by "unknown".  Clinton didn't declare his candidacy until late 1991, but even by early 1991, he was considered a likely presidential candidate (heck, even as far back as 1989, he was considered a likely presidential candidate).  He was unknown to the general public, but he certainly would have been known to the politically informed by early 1991.....at *least* as much as Mike Huckabee was known in early 2007.

Incidentally, Bill claimed while campaigning for his wife last year that he decided not to run for the '88 nomination the day before he was supposed to announce his plans. Smart man...

[The Ex-Factor]

Obama's strongest opponents for the '12 nomination will probably be Lady Lynn de Rothschild and Mike Gravel.

[The Ex-Factor]

There are always the Lyndon LaRouches around to prevent sitting presidents getting 100% in primaries

And I'm aware Gravel left the party, but I couldn't think of any other kooks in the party who would run again. Not even Kucinich.