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| Adams | Obama | 56.9% | 100,649 | | | Romney | 40.1% | 70,972 | | | Other | 3.0% | 5,272 | |
| Alamosa | Obama | 56.8% | 3,811 | | | Romney | 40.3% | 2,705 | | | Other | 3.0% | 199 | |
| Arapahoe | Obama | 53.9% | 153,905 | | | Romney | 44.0% | 125,588 | | | Other | 2.1% | 6,023 | |
| Archuleta | Obama | 39.8% | 2,679 | | | Romney | 57.5% | 3,872 | | | Other | 2.7% | 183 | |
| Baca | Obama | 22.2% | 467 | | | Romney | 74.0% | 1,559 | | | Other | 3.8% | 80 | |
| Bent | Obama | 42.0% | 815 | | | Romney | 55.4% | 1,075 | | | Other | 2.7% | 52 | |
| Boulder | Obama | 69.7% | 125,091 | | | Romney | 27.8% | 49,981 | | | Other | 2.5% | 4,427 | |
| Broomfield | Obama | 51.6% | 16,966 | | | Romney | 45.7% | 15,008 | | | Other | 2.7% | 891 | |
| Chaffee | Obama | 48.6% | 5,086 | | | Romney | 48.5% | 5,070 | | | Other | 2.9% | 306 | |
| Cheyenne | Obama | 15.7% | 172 | | | Romney | 81.3% | 889 | | | Other | 2.9% | 32 | |
| Clear Creek | Obama | 54.3% | 3,119 | | | Romney | 42.3% | 2,430 | | | Other | 3.4% | 194 | |
| Conejos | Obama | 54.0% | 2,213 | | | Romney | 44.7% | 1,835 | | | Other | 1.3% | 53 | |
| Costilla | Obama | 72.9% | 1,340 | | | Romney | 24.3% | 446 | | | Other | 2.8% | 51 | |
| Crowley | Obama | 35.6% | 535 | | | Romney | 61.5% | 924 | | | Other | 2.9% | 43 | |
| Custer | Obama | 32.0% | 868 | | | Romney | 65.9% | 1,788 | | | Other | 2.2% | 59 | |
| Delta | Obama | 29.0% | 4,622 | | | Romney | 68.5% | 10,915 | | | Other | 2.4% | 388 | |
| Denver | Obama | 73.4% | 222,018 | | | Romney | 24.2% | 73,111 | | | Other | 2.4% | 7,289 | |
| Dolores | Obama | 26.8% | 334 | | | Romney | 69.0% | 859 | | | Other | 4.2% | 52 | |
| Douglas | Obama | 36.3% | 61,094 | | | Romney | 62.1% | 104,397 | | | Other | 1.5% | 2,593 | |
| Eagle | Obama | 56.4% | 12,792 | | | Romney | 41.5% | 9,411 | | | Other | 2.1% | 465 | |
| Elbert | Obama | 25.4% | 3,603 | | | Romney | 72.4% | 10,266 | | | Other | 2.2% | 309 | |
| El Paso | Obama | 38.5% | 111,819 | | | Romney | 58.9% | 170,952 | | | Other | 2.6% | 7,404 | |
| Fremont | Obama | 32.8% | 6,704 | | | Romney | 64.5% | 13,174 | | | Other | 2.6% | 538 | |
| Garfield | Obama | 46.3% | 11,305 | | | Romney | 51.4% | 12,535 | | | Other | 2.3% | 568 | |
| Gilpin | Obama | 56.7% | 1,892 | | | Romney | 40.3% | 1,346 | | | Other | 3.0% | 100 | |
| Grand | Obama | 45.0% | 3,684 | | | Romney | 51.9% | 4,253 | | | Other | 3.1% | 250 | |
| Gunnison | Obama | 58.2% | 5,044 | | | Romney | 38.5% | 3,341 | | | Other | 3.3% | 282 | |
| Hinsdale | Obama | 38.2% | 229 | | | Romney | 58.8% | 353 | | | Other | 3.0% | 18 | |
| Huerfano | Obama | 52.5% | 1,953 | | | Romney | 44.2% | 1,646 | | | Other | 3.3% | 124 | |
| Jackson | Obama | 25.5% | 216 | | | Romney | 70.8% | 600 | | | Other | 3.8% | 32 | |
| Jefferson | Obama | 51.2% | 159,296 | | | Romney | 46.4% | 144,197 | | | Other | 2.4% | 7,559 | |
| Kiowa | Obama | 14.4% | 118 | | | Romney | 82.5% | 677 | | | Other | 3.2% | 26 | |
| Kit Carson | Obama | 22.6% | 838 | | | Romney | 75.2% | 2,785 | | | Other | 2.1% | 79 | |
| Lake | Obama | 60.5% | 1,839 | | | Romney | 36.1% | 1,098 | | | Other | 3.4% | 103 | |
| La Plata | Obama | 52.8% | 15,489 | | | Romney | 43.7% | 12,794 | | | Other | 3.5% | 1,025 | |
| Larimer | Obama | 51.5% | 92,747 | | | Romney | 45.7% | 82,376 | | | Other | 2.8% | 5,057 | |
| Las Animas | Obama | 50.2% | 3,445 | | | Romney | 47.6% | 3,263 | | | Other | 2.2% | 154 | |
| Lincoln | Obama | 24.1% | 552 | | | Romney | 73.8% | 1,687 | | | Other | 2.1% | 48 | |
| Logan | Obama | 29.7% | 2,712 | | | Romney | 67.7% | 6,179 | | | Other | 2.6% | 233 | |
| Mesa | Obama | 32.7% | 23,846 | | | Romney | 65.1% | 47,472 | | | Other | 2.2% | 1,629 | |
| Mineral | Obama | 44.8% | 291 | | | Romney | 52.9% | 344 | | | Other | 2.3% | 15 | |
| Moffat | Obama | 21.6% | 1,330 | | | Romney | 76.1% | 4,695 | | | Other | 2.3% | 143 | |
| Montezuma | Obama | 36.9% | 4,542 | | | Romney | 60.1% | 7,401 | | | Other | 3.0% | 375 | |
| Montrose | Obama | 30.5% | 6,138 | | | Romney | 67.3% | 13,552 | | | Other | 2.2% | 440 | |
| Morgan | Obama | 36.3% | 3,912 | | | Romney | 61.3% | 6,602 | | | Other | 2.4% | 263 | |
| Otero | Obama | 44.5% | 3,647 | | | Romney | 53.5% | 4,382 | | | Other | 2.0% | 163 | |
| Ouray | Obama | 51.4% | 1,646 | | | Romney | 46.3% | 1,481 | | | Other | 2.3% | 75 | |
| Park | Obama | 41.2% | 3,862 | | | Romney | 55.9% | 5,236 | | | Other | 2.9% | 268 | |
| Phillips | Obama | 26.0% | 588 | | | Romney | 72.3% | 1,637 | | | Other | 1.8% | 40 | |
| Pitkin | Obama | 68.0% | 6,849 | | | Romney | 30.0% | 3,024 | | | Other | 2.0% | 202 | |
| Prowers | Obama | 31.2% | 1,519 | | | Romney | 66.4% | 3,230 | | | Other | 2.3% | 114 | |
| Pueblo | Obama | 55.7% | 42,551 | | | Romney | 41.7% | 31,894 | | | Other | 2.6% | 1,974 | |
| Rio Blanco | Obama | 16.9% | 568 | | | Romney | 80.9% | 2,724 | | | Other | 2.3% | 77 | |
| Rio Grande | Obama | 44.8% | 2,478 | | | Romney | 52.7% | 2,918 | | | Other | 2.5% | 137 | |
| Routt | Obama | 56.7% | 7,547 | | | Romney | 41.1% | 5,469 | | | Other | 2.3% | 301 | |
| Saguache | Obama | 63.6% | 1,864 | | | Romney | 32.9% | 964 | | | Other | 3.5% | 102 | |
| San Juan | Obama | 52.6% | 266 | | | Romney | 41.9% | 212 | | | Other | 5.5% | 28 | |
| San Miguel | Obama | 70.3% | 2,992 | | | Romney | 27.1% | 1,154 | | | Other | 2.6% | 110 | |
| Sedgwick | Obama | 31.3% | 419 | | | Romney | 65.8% | 881 | | | Other | 2.8% | 38 | |
| Summit | Obama | 61.0% | 9,347 | | | Romney | 36.4% | 5,571 | | | Other | 2.6% | 394 | |
| Teller | Obama | 32.3% | 4,333 | | | Romney | 64.9% | 8,702 | | | Other | 2.8% | 372 | |
| Washington | Obama | 18.1% | 468 | | | Romney | 80.1% | 2,076 | | | Other | 1.8% | 47 | |
| Weld | Obama | 42.2% | 49,050 | | | Romney | 54.8% | 63,775 | | | Other | 3.0% | 3,466 | |
| Yuma | Obama | 21.6% | 987 | | | Romney | 76.3% | 3,490 | | | Other | 2.2% | 100 | |
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