Collins and Graham, Graham may just retire to avoid losing (SC GOP is too far right for him at this point), and Collins may have an issue where she appeals to the Maine electorate as a whole, but not the ME GOP electorate.. same issue Mike Castle had in Delaware..
I think Alexander (and Sessions) hold only because they have been around a while, aren't terribly unpopular, and the TN GOP isn't that Tea Party controlled( Corker didn't face any significant opposition)
I'm guessing Alexander and Graham, possibly Collins.