What would your 2006 U.S. Senate strategy be?

[Snowe08]

Here are my challenger candidates in each state.
ME - Run a strawman.  She's gonna crush whoever it is.

No kidding. Snowe won in 2000 - against a not entirely unpopular State Senate President, Mark Lawrence - with nearly 70% of the vote, and in over thirty years of elected office, she has never lost an election. Chris Potholm, in An Insider's Guide to Maine Politics: 1946-1996, called her "the standard against which all post-war political figures must be judged in terms of electoral success."

[Snowe08]

TX, UT, IN are safe seats even with retirements, no need to invest money there.

That's a really crappy way of thinking.  Indiana has one Democratic Senator already; it's not impossible to get another one.

On the other hand, Indiana is a deep red state, which - after the last election - has a Republican governor and Republican control of both houses of its state legislature. Bayh's re-election is an affirmation of the power of incumbency, rather than an affirmation of Indiana's vulnerability to a Democratic candidate.