President Barack Obama/Joe Biden VS Mitt Romney/Rob Portman

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Not voting this year.  But Portman gives Romney a real shot at winning Ohio.  The auto-bailouts and falling unemployment make it possible that Obama can hold Ohio, and without Ohio, it's a lot harder to put together a winning electoral map for Romney in a close race.  Besides, Portman is smart, capable, and a good deal-maker, all very valuable traits in a VP.  In the race, you don't want someone who draws voltage out of the top of the ticket, but do want someone who can help you in a crucial region.