Most centrist major cities

[Sam Spade]

I think it really depends on what you would define as a "city".

Is a "city" just the "inner city", or is it the "entire area within the city limits", including suburbs, or does it include the whole "metropolitan" area"?

For example, most major cities in Texas (Houston, Dallas, San Antonio, even El Paso) if you define it as "inner city" are liberal, if you define the "entire area within the city limits" are centrist (lots of liberals and conservatives) and if you include the whole "metropolitan area" are conservative (because of the right-of-Attila-the-Hun quality of suburbs and exurbs in Texas).

The only main exception to this in Texas I can think of is Austin, where the "metropolitan area" is centrist and the rest are liberal.