Most centrist major cities

[Alcon]

The downtown, the city as a whole, or the metro area?

[Alcon]

Cincinnati?? Denver?? Im not sure,

Danver is quite liberal (socially especially) I would probably go with Indianapolis

Even if you take all the surounding counties (suburbs, which are comfortably Republican), the five-county area of Denver is still liberal overall.  It takes the entire rest of the state to balance Denver and give Republicans a moderate lead.

Here's some guesses for me, but I don't have much first-hand knowledge:
San Diego, CA
Sacramento, CA
Phoenix, AZ
Oklahoma City, OK
Reno, NV

San Diego the city, as opposed to the military base, leans slightly left but is very moderate.

Sacramento leans slightly left, but is probably a great candidate.

Phoenix the city is left-leaning. The suburbs are rightist.

Oklahoma City is right-leaning.

Reno is pretty centrist.

I also add to the list Dallas, TX.

[Alcon]

I suppose that is true, JNB.

This is the exact problem - most downtowns of major cities are heavily Democratic. There are some exceptions (Provo, UT) but they are in the minority.

[Alcon]

The conservatives might claim that it is Salt Lake City.
Newt Gingrich: “We are the center”

SLC is actually pretty liberal.

Maybe. Maybe not.

Unless you know something we don't, Salt Lake County has not released precinct data. But the county itself was 60-38 Bush. That hardly suggests SLC itself is liberal, but maybe moderate. Downtown SLC might have voted Kerry.