It is hard to argue for Rajoy to go since this is the third election in a row where he led PP to be the largest party in terms of seats and votes.
In the most recent poll I could find, Rajoy's net approval rating was -44. He has presided over a large number of corruption scandals. He's even been declared persona non grata by his hometown legislature. No leader with an ounce of sense will ever agree to join him in government. C's, especially, would suffer with the voters who chose them as an alternative to PP and PSOE corruption and aren't willing to support PODEMOS radicalism.