There are going to be many ads referring to Hillary putting the Pubs at the top of her enemies list. My sense is that she said it jocularly, but the Pubs aren't laughing (maybe smiling at the unforced error and its exploitability, but not laughing).
I think you can actually sort of see it on her face that she immediately regretted saying it for that very reason. She keeps laughing through it, but as she begins to look down you can almost see a flash of "oops."
But maybe I'm thinking I'm seeing something that's really not there.
Dems should actually take heart, as it could have been much much worse: as the last "enemy" on her list, Mrs. Clinton could have said "the people over at the FBI"...