the 1920 election is normally interpreted as a reaction against the activisim and zeal of the Teddy Roosevelt/Wilson era (even if they were both from different parties and had Taft in the middle of them).
And 1876 is another good example: after 8 years of Grant, the Dems managed to seize enough Union states to win the "popular vote" (with the help of their paramilitaries).
1896 was a near-win for the Free Silver faction of Democrats and a win for Republicans thanks to fatigue from 12 years of Bourbon Democratic influence [even with Benjamin Harrison in the middle]