Here's my wild guess at what the map will look like in 2052.
The "Sandersization" of the Democratic Party takes effect and the Democrats become a much more economically populist party. West Virginia and Kentucky drift back to their Democratic roots. Meanwhile, with a growing African-American population in the south, the states of Mississippi and Georgia go from red, to purple, and then to solid Democratic. Texas, now a majority Latino state, is also a tossup, with the Republican Party moving to the center on social issues over the past few decades and making some inroads with Latinos post-Trump. The 2052 Republican Party also has made inroads with college educated whites and Asians as well, making the party competitive in the northeast once-more (this is all due to the United States now being a majority-minority country and the Republicans having to shift to a socially centrist platform or else fade into obscurity).
Either way, its too soon to tell what the electoral map will be.
