Nixon/Agnew (R) 456 EVMcGovern/Shriver (D) 42 EVThe question is framed a bit improperly. Of the three (3) "Amnesty, Abortion, and Acid" issues, only Amnesty was a major issue in the fall campaign.
Roe v Wade hadn't been decided yet, and abortion was not on the public consciousness as a social issue to the degree that School Busing to achieve racial integration was. BUSING, and not abortion, was the hottest of hot-button issues in 1972; it was the issue that caused McGovern to lose Michigan and Maryland, states that were Democratic even then.
Nixon ran up larger than normal majorities in Northern suburbs mainly due to the issue of court-ordered cross-district busing to achieve racial integration in public schools. This is the issue that pushed the Detroit suburbs into the GOP column (they had been rather Democratic before 1972). It was what pushed suburban Baltimore County (and even the DC suburbs) into the GOP column. The question is really whether or not a National Democrat could have volubly opposed Busing while maintaining the level of black support that they needed to win.