Yes, and no.
The objection in Arizona was not to redistricting commissions. It was that the commission would have had to be established by the legislature, not by referendum. I think that could go, but a commissioned established by the legislature, even one whose members are chosen directly by the electorate, would remain.
That would be the equivalent of striking them down, since a gerrymandered legislature would never accept a redistricting commission against its own interests.
No, if the electorate makes redistricting the prime issue in state elections. The voters can vote out anyone opposing a redistricting commission. Now, if the voters decide they don't want a commission, they can vote for candidates that oppose it.