Well this is an interesting question.
Frist would be a contender but only under certain circumstances. The question is if Gore won would Trent Lott have been booted from his spot as Senator Minority Leader? If he did retain that spot Frist would not be in the picture at all.
George W. Bush would be in there for sure more then likely because he almost beat Gore and would more then likely pick someone from Florida to be his running mate.
Jeb would be considered to run aginst Gore but I think George would still get first dibs to run and Jeb would sit out.
McCain is another name that comes to mind even though he did say he wouldn't run again he might reconsider that under certain conditions
But theres one person who could be a major player in this case Rudy Giuliani "America's Mayor" would be a hard candidate to beat.
Colin Powell would also be in the runnings as well and I'd say it would be a 3 way race between Powell, Giuliani and Bush to get the nomination.
As others have said, Gore probably would be less popular then Bush is right now due to the fact he wouldn't have gone into Iraq(not to mention Libya would not have ended their weapons program and N.Korea would also be a much bigger topic) but under a lot of pressure would have probably reluctantly gone into Afgahnistan.
Gore is a nice guy and all but I think he more then likely would have lost in '04 if he had pulled it out in 2000
Plus, with Gore as president, people would be more inclined to blame the ressession (which has been long over) on Clinton and the Democrats wouldn't have anyone to scape-goat for it.