Democrats will lose in NC, SC, GA, FL, and probably LA. They can only hope to pull upsets out west to prevent a complete rout.
I'd bet real money that you're wrong. LA is lean Dem. The Dems will probably win, not loose. GA and SC are going to switch, but so are CO and IL so the senate won't change from that. NC and FL are up in the air, as are AK and OK. There is a good chance that the senate stays 51-49. There is also a good chance that the Dems win OK and AK while holding NC and FL. Likewise there is an equal chance that the GOP wins NC and FL while holding OK and AK.