Obama's only problem is that Clinton Inc is in a corner now and they are going to come after him with everything they've got. He will be bloodied some before the convention and thus he's at his peak in popularity now - 8 months before the GE. She'll wound him. How much, we'll have to see.
But what can she throw at him that she hasn't already? She and Bill played the race card and it backfired, they spread rumors that he was a Muslim and did everything short of calling him "Barack Muhammad Hussein Obama" to drive home the point. They went progressively more negative and it backfired. She sent Bill out to campaign for the black vote and it failed. The flipside of Obama's relative lack of experience in elected office is that he has few or no scandals: the Rezko thing is flimsy at best and nobody cares that he did drugs when he was a teenager.